| ncRNA name | hsa-miR-193a |
| ncRNA Category | miRNA |
| Disease name | age-related cataract |
| Species | Homo sapiens |
| Tissues/Cell_line | lens epithelium samples; human lens epithelial cells (HLECs) |
| Methods | transfection, MTT assay, Calcein-AM and PI staining, Rhodamine 123 and Hoechst 33342 staining, EdU incorporation assay, luciferase reporter assay, Western blot |
| Expression pattern | up-regulated |
| Functional description | miR-193a regulates CRYAA expression by targeting the binding site within the 3'UTR. Moreover, miR-193a decreases the viability and proliferation, and increases the apoptosis of HLECs upon oxidative stress. |
| PubMed ID | 29959922 |
| Year | 2018 |
| Title | Circular RNA HIPK3 regulates human lens epithelial cells proliferation and apoptosis by targeting the miR-193a/CRYAA axis. |
| Drug-related ncRNA | NO |
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